Method for Coating A Medical Device, Especially for Fabrication of Antithrombogenic and Antibacterial Titanium Materials and Their Alloys
| Publication Number: |
EP4467167A1 |
| Application Date: |
25. 5. 2023 |
| Assignee/Applicant: |
Jožef Stefan Institute [SI], University of Ljubljana |
| Inventor: |
Junkar Ita; Bencina Metka; Rawat Niharika; Markovic Gaja; Stanic Jan; Kralj-Iglic Veronika; Iglic Ales |
| Title: |
Method for Coating A Medical Device, Especially for Fabrication of Antithrombogenic and Antibacterial Titanium Materials and Their Alloys |
| Description: |
The method for treatment of Ti and Ti alloys used for implants, especially vascular stents, is provided. The method comprises of two steps, where the first step is based on electrochemical anodisation with atmospheric plasma electrode in environment friendly liquid and the second step where UV irradiation of the substrate is used to activate the surface. In the first step, the surface of titanium and titanium alloys is oxidised and micro/nanostructured and it the second step surface is activated to assure more optimal biological response.The methods of invention enable formation of nanostructured titanium oxide layer on the surface of titanium and titanium alloys with improved biocompatibility/hemocompatibility against state of the art. This innovative approach reduces adhesion and activation of platelets and at the same time reduces bacterial adhesion. |
| Drawings: |
 |
| Category: |
Nanotechnology and New Materials |
| Technology application codes: |
Industrial manufacturing, material and transport, Biological sciences |
| Market application codes: |
Medical / health related, Computer related |
| www: |
https://worldwide.espacenet.com/patent/search/family/086604780/publication/EP4467167A1?q=pn%3DEP4467167A1 |
| Patent offices: |
WIPO |
