Method for Treatment of Medical Metals and Their Alloys
| Publication Number: |
EP4049690C0 |
| Application Date: |
25. 2. 2021 |
| Assignee/Applicant: |
Jožef Stefan Institute [SI] |
| Inventor: |
Ita Junkar; Metka Bencina; Rok Zaplotnik; Miran Mozetic; Snezana Sodin-Semrl; , Katja Lakota; Ales Iglic |
| Title: |
Method for Treatment of Medical Metals and Their Alloys |
| Description: |
The method for treatment metals and metal alloys used for implants, especially vascular stents, is provided. The method comprises of three combined steps, including the first plasma-treatment step, the hydrothermal treatment and the second plasma-treatment step. The first plasma-treatment step assures for a contaminant-free surface with high surface energy, which in turn enables nucleation sites of appropriate properties for depositing a nano-structured film of titanium oxide. The next step is the deposition of a titanium oxide film. The second step is preferably performed within 10 to 1000 s after the first plasma treatment to minimise the risk of spontaneous hydrophobic recovery. The as-deposited materials are further treated by the second plasma treatment, which assures for appropriate surface finish and crystallinity of the thin nano-structured titanium oxide film. The methods of invention enable the formation of the titanium oxide layer on the surface of metals or alloys with improved biocompatibility/hemocompatibility against state of the art. |
| Drawings: |
 |
| Category: |
Nanotechnology and New Materials |
| Technology application codes: |
Industrial manufacturing, material and transport, Biological sciences |
| Market application codes: |
Medical / health related, Computer related |
| www: |
https://worldwide.espacenet.com/patent/search/family/074758620/publication/EP4049690C0?q=pn%3DEP4049690A1 |
| Patent offices: |
WIPO |
