Method for Immobilization of Heparin on a Polymeric Material
| Publication Number: |
EP2997984B1 |
| Application Date: |
17. 9. 2015 |
| Assignee/Applicant: |
Jožef Stefan Institute [SI], University of Maribor [SI] |
| Inventor: |
Metod Kolar, Alenka Vesel, Martina Modic, Ita Junkar, Karin Stana – Kleinschek, Miran Mozetič |
| Title: |
Method for Immobilization of Heparin on a Polymeric Material |
| Description: |
The present invention refers to a method for immobilization of heparin on polymeric material, said method comprising selecting a substrate made from a polymeric material, pre-treating said substrate, mounting said substrate into a vacuum chamber, evacuating the vacuum chamber to pressure essentially below 100 Pa, preferably below 1 Pa, selecting a source of NH2 radicals, leaking the NH2 radicals from said source into said vacuum chamber during continuous pumping of said vacuum chamber, interacting said NH2 (NH2) radicals with said substrate made from a polymeric material, evacuating said vacuum chamber, venting said vacuum chamber to atmospheric pressure, and covalent bonding of activated heparin on said substrate. |
| Drawings: |
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| Category: |
Nanotechnology and New Materials |
| Technology application codes: |
Physical and exact sciences, Measurements and standards |
| Market application codes: |
Medical / health related, Industrial products |
| www: |
https://worldwide.espacenet.com/patent/search/family/051869176/publication/EP2997984B1?q=EP2997984 |
| Patent offices: |
EPO |
