Modified Food Grade Microorganism for Treatment of Inflammatory Bowel Disease
| Publication Number: | EP2521737B1 |
| Application Date: | 5. 1. 2011 |
| Assignee/Applicant: | Jožef Stefan Institute [SI], Labena d. o. o. [SI], University of Ljubljana [SI] |
| Inventor: | Aleš Berlec, Boris Čeh, Mojca Lunder, Matjaž Ravnikar, Borut Štrukelj |
| Title: | Genetically Modified Food Grade Microorganism for Treatment of Inflammatory Bowel Disease |
| Description: | The present invention relates to genetically modified microorganisms that express TNF± binding polypeptide on their surface. Peptides expressed on the surface of microorganism are more resistant to chemical and enzymatic degradation in the gastrointestinal tract. Such microorganisms are capable of binding TNF± and therefore reducing the content of free TNF± and alleviating its pro-inflammatory effects in the gut. Such microorganisms can be used as medicament in the treatment of inflammatory bowel disease. |
| Drawings: |  |
| Category: | Biological Sciences |
| Technology application codes: | Biological sciences |
| Market application codes: | Medical / health related, Genetic engineereing / molecluar biology |
| www: | https://worldwide.espacenet.com/patent/search/family/041786343/publication/EP2521737B1?q=%20EP2521737B1 |
| Patent offices: | EPO |
Extended patent application
| Publication Number: | WO2011083080A1 |
| Application Date: | 5. 1. 2011 |
| Assignee/Applicant: | Jožef Stefan Institute [SI], Labena d. o. o. [SI], University of Ljubljana [SI], Aleš Berlec [SI], Boris Čeh [SI], Mojca Lunder [SI], Matjaž Ravnikar [SI], Borut Štrukelj [SI] |
| Inventor: | Aleš Berlec, Boris Čeh, Mojca Lunder, Matjaž Ravnikar, Borut Štrukelj |
| Title: | Modified Food Grade Microorganism for Treatment of Inflammatory Bowel Disease |
| www: | https://worldwide.espacenet.com/patent/search/family/041786343/publication/WO2011083080A1?q=pn%3DWO2011083080A1 |
Extended patent application
| Publication Number: | US8754198B2 |
| Application Date: | 5. 1. 2011 |
| Assignee/Applicant: | Jožef Stefan Institute [SI], Labena d. o. o. [SI], University of Ljubljana [SI], Aleš Berlec [SI], Boris Čeh [SI], Mojca Lunder [SI], Matjaž Ravnikar [SI], Borut Štrukelj [SI] |
| Inventor: | Aleš Berlec, Boris Čeh, Mojca Lunder, Matjaž Ravnikar, Borut Štrukelj |
| Title: | Modified Food Grade Microorganism for Treatment of Inflammatory Bowel Disease |
| www: | https://worldwide.espacenet.com/patent/search/family/041786343/publication/US8754198B2?q=%20US8754198B2 |