Modified Food Grade Microorganism for Treatment of Inflammatory Bowel Disease | Project and Innovation Support
15/01/2021

Modified Food Grade Microorganism for Treatment of Inflammatory Bowel Disease

Publication Number: EP2521737B1
Application Date: 5. 1. 2011
Assignee/Applicant: Jožef Stefan Institute [SI], Labena d. o. o. [SI], University of Ljubljana [SI]
Inventor: Aleš Berlec, Boris Čeh, Mojca Lunder, Matjaž Ravnikar, Borut Štrukelj
Title: Genetically Modified Food Grade Microorganism for Treatment of Inflammatory Bowel Disease
Description: The present invention relates to genetically modified microorganisms that express TNF± binding polypeptide on their surface. Peptides expressed on the surface of microorganism are more resistant to chemical and enzymatic degradation in the gastrointestinal tract. Such microorganisms are capable of binding TNF± and therefore reducing the content of free TNF± and alleviating its pro-inflammatory effects in the gut. Such microorganisms can be used as medicament in the treatment of inflammatory bowel disease.
Drawings:
Category: Biological Sciences
Technology application codes: Biological sciences
Market application codes: Medical / health related, Genetic engineereing / molecluar biology
www: https://worldwide.espacenet.com/patent/search/family/041786343/publication/EP2521737B1?q=%20EP2521737B1
Patent offices: EPO

 

Extended patent application


Publication Number: WO2011083080A1
Application Date: 5. 1. 2011
Assignee/Applicant: Jožef Stefan Institute [SI], Labena d. o. o. [SI], University of Ljubljana [SI], Aleš Berlec [SI], Boris Čeh [SI], Mojca Lunder [SI], Matjaž Ravnikar [SI], Borut Štrukelj [SI]
Inventor: Aleš Berlec, Boris Čeh, Mojca Lunder, Matjaž Ravnikar, Borut Štrukelj
Title: Modified Food Grade Microorganism for Treatment of Inflammatory Bowel Disease
www: https://worldwide.espacenet.com/patent/search/family/041786343/publication/WO2011083080A1?q=pn%3DWO2011083080A1

 

Extended patent application


Publication Number: US8754198B2
Application Date: 5. 1. 2011
Assignee/Applicant: Jožef Stefan Institute [SI], Labena d. o. o. [SI], University of Ljubljana [SI], Aleš Berlec [SI], Boris Čeh [SI], Mojca Lunder [SI], Matjaž Ravnikar [SI], Borut Štrukelj [SI]
Inventor: Aleš Berlec, Boris Čeh, Mojca Lunder, Matjaž Ravnikar, Borut Štrukelj
Title: Modified Food Grade Microorganism for Treatment of Inflammatory Bowel Disease
www: https://worldwide.espacenet.com/patent/search/family/041786343/publication/US8754198B2?q=%20US8754198B2