Method of Treatment of Biomedical Polymeric Prostheses for Improvement of Their Antithrombogenous Properties
| Publication Number: | SI23021A |
| Application Date: | 20. 4. 2009 |
| Assignee/Applicant: | Jožef Stefan Institute [SI] |
| Inventor: | Uroš Cvelbar, Dragoslav Domanović, Ita Junkar, Metka Krašna, Miran Mozetič, Alenka Vesel |
| Title: | Metoda obdelave bio-medicinskih polimernih protez za izboljšanje njihovih antitrombogenih lastnosti [SL], Method of Treatment of Biomedical Polymeric Prostheses for Improvement of Their Antithrombogenous Properties [EN] |
| Description: | The subject of the invention is a method of treatment of biomedical prostheses for improvement of their antithrombogenous properties. The mentioned biomedical prostheses are the cardiovascular ones, particularly artificial veins and stents made of polyethyleneterephtalate (PET) polymer. The method is based on treatment of cardiovascular prosthesis surface with a suitable combination of dose of neutral oxygen atoms and positively charged molecular and atomic oxygen ions. After the dose of said atoms and ions has been received, the surface of cardiovascular prostheses becomes less susceptible to bonding of thrombocytes. The method is characterised in that the exposedness to the mixture of neutral oxygen atoms and positively charged molecular and atomic oxygen ions in pulses is such that in an individual pulse, the achieved dose of neutral oxygen atoms amounts to between 10exp20/ m2 and 10exp26/m2 and the dose of charged molecular and atomic oxygen ions to between 10exp16/m2 and 10exp23/m2 with time intervals between individual pulses lasting between 10 s and 300 s, and that the stream of neutral oxygen atoms and positively charged molecular and atomic oxygen ions onto the surface of the prosthesis is approximately uniform. |
| Drawings: |  |
| Category: | Physical Sciences |
| Technology application codes: | Physical and exact sciences, Biological sciences |
| Market application codes: | Medical / health related |
| www: | https://worldwide.espacenet.com/patent/search/family/042246151/publication/SI23021A?q=si23021 |
| Patent offices: | UIL RS |
Extended patent application
| Publication Number: | WO2010123465A3 |
| Application Date: | 18. 3. 2010 |
| Assignee/Applicant: | Jožef Stefan Institute [SI], Uroš Cvelbar [SI], Dragoslav Domanović [SI], Ita Junkar [SI], Metka Krašna [SI], Miran Mozetič [SI], Alenka Vesel [SI] |
| Inventor: | Uroš Cvelbar, Dragoslav Domanović, Ita Junkar, Metka Krašna, Miran Mozetič, Alenka Vesel |
| Title: | Method of Treatment of Biomedical Polymeric Prostheses for Improvement of Their Antithrombogenous Properties |
| www: | https://worldwide.espacenet.com/patent/search/family/042246151/publication/WO2010123465A3?q=WO2010123465A3 |
Extended patent application
| Publication Number: | AT513072B1 |
| Application Date: | 18. 3. 2010 |
| Assignee/Applicant: | Jožef Stefan Institute [SI] |
| Inventor: | Uroš Cvelbar, Dragoslav Domanović, Ita Junkar, Metka Krašna, Miran Mozetič, Alenka Vesel |
| Title: | Verfahren Zur Behandlung Biomedizinischer Implantate Zur Verbesserung Deren Antithrombogener Eigenschaften |
| www: | https://worldwide.espacenet.com/patent/search/family/042246151/publication/AT513072B1?q=pn%3DAT513072B1 |