Crystal structure of staphylococcus aureus autolysin e, method of producing the crystal and its use in screening methods

Publication Number: WO2016173603A1
Application Date: 27. 04. 2015
Assignee/Applicant: Jožef Stefan Institute [SI]
Inventor:
Marko Mihelič, Miha Renko, Dušan Turk
Title: Crystal structure of staphylococcus aureus autolysin e, method of producing the crystal and its use in screening methods
Description: The invention concerns the determination and evaluation of the crystal structure of autolysin E (AtlE) of Staphylococcus aureus (S. aureus), or a crystallizable fragment of AtlE, a method for producing a crystal of AtlE and the respective crystallization kit, and its use in a method for screening an inhibitor of the N-acetylglucosaminidase activity of AtlE, for obtaining atomic spatial relationship data, and for identifying a binding compound of AtlE, e.g. by in silico screening.
Drawings: /
Category: Biological sciences
Technology application codes: Biological sciences
Market application codes: Genetic engineering/ Molecular biology
www: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016173603
Patent offices: WIPO

Extended patent application

Publication Number: CA2982368A1
Application Date: 27. 04. 2015
Assignee/Applicant: Jožef Stefan Institute [SI]
Inventor:
Marko Mihelič, Miha Renko, Dušan Turk
Title: Crystal structure of staphylococcus aureus autolysin e, method of producing the crystal and its use in screening methods
www: https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20161103&DB=&locale=en_EP&CC=CA&NR=2982386A1&KC=A1&ND=5